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Integrated Transcription Factor Platform |
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| No. | Question |
| 1 | What is ITFP? |
| 2 | SiteMap of ITFP |
| 3 | What method and material are used in ITFP to obtain TF and target pairs? |
| 4 | How do I cite ITFP? |
| 5 | How can I download the data of ITFP? |
| 1 What is ITFP? |
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| 3 What method and material are used in ITFP to obtain TF and target pairs? |
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In our work, a reverse engineering method named ARACNE was used to derive potential interaction pairs between transcription factor and downstream regulated gene from Human, Mouse and Rat gene expression profile data.
Here, we collected gene expression profile data from Affymetrix human Genome U133 plus 2.0 Array platform, Affymetrix mouse Genome 430 2.0 Array platform, and Affymetrix rat Genome 230 2.0 Array platform respectively in GEO database. Finally, three gene expression profile datasets containing 302 (22 tissues), 310 (34 tissues), and 332 (39 tissues) samples were built for Human, Mouse, and Rat respectively. Here is datailed information of the three datasets: Human , Mouse , Rat . |
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| 4 How do I cite ITFP? |
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| 5 How can I downlaod data of the ITFP? |
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| if you use data of ITFP, please cite articles mentioned above | |
| if you are a non-commercial user, you can get data from here | |
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| &CopyRight 2008 Bioinformation Center,ShangHai Institutes for Biological Sciences. DM group, Fudan University |
| Bioinformation Center |
| Data Mining group |